Improving Lives Around The World Through Lymphatic System Research and Education

Lymphatic Research & Education Institute

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Research Associated with Autism - Lymphatic System Study

In June of 2015 researchers at the University of Virginia found lymphatic vessels in the brain of mice. This is a direct lymph-brain connection. They said this will have profound implications when looking at diseases of the brain. See study.

In 2017 researchers found that the major outflow of cerebrospinal fluid is through lymphatic vessels. See article.

Before lymphatic vessels were found in the brain, it was known that a portion of cerebrospinal fluid was absorbed by the extracranial (outside of cranium) lymphatic system.  There is no doubting now, that the brain is dependent on a healthy lymphatic system. 

Excess Cerebrospinal Fluid Detectable at 6 Months in High-risk Infants Who Develop ASD

Numerous studies confirm and extend previous findings that increased extra-axial CSF is detectable at 6 months in high-risk infants who develop ASD. 

(1) Early brain enlargement and elevated extra-axial fluid in infants who develop autism spectrum disorder. Mark D. Shen, Christine W. Nordahl, Gregory S. Young, Sandra L. Wootton-Gorges, Aaron Lee, Sarah E. Liston, Kayla R. Harrington, Sally Ozonoff, David G. Amaral

Brain, Volume 136, Issue 9, September 2013, Pages 2825–2835, 
(2) Increased Extra-axial Cerebrospinal Fluid in High-Risk Infants Who Later Develop Autism

Mark D. Shen… Biological Psychiatry August 1, 2017Volume 82, Issue 3, Pages 186–193

(3)  Cerebrospinal fluid and the early brain development of autism.  Shen, M.D.  J Neurodevelop Disord 10, 39 (2018).                                                                                                                                                        


Autism / Lymph-Brain Connection Study

"I am a big believer in early intervention."

-Temple Grandin

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​​Lymphatic Research and Education Institute's

Autism - Lymphatic System Study

6 years old & younger - 5 Case Studies

In this study, we are trying to show how activating the superficial and deep lymphatic system, with extra lymphatic activation in the clavicles, neck, mouth, face, and cranium can improve the Lymph-Brain Connection. This improved circulation improves natural detoxification of acidic wastes and cerebrospinal fluid from the body and brain. We hope to show how improving lymph flow, in children with ASD, can help to alleviate a buildup of acidic cellular waste and cerebrospinal fluid to help cognitive function, digestive issues and skin problems. We are starting with five case studies.

Important Lymph-Brain Connection

New research in June of 2015 found lymphatic vessels in the brain. That means there is a direct lymphatic system-brain connection. In 2017 researchers found that the major outflow of cerebrospinal fluid is through lymphatic vessels. The lymphatic system helps to maintain every system in the body, even the brain, and its many structures. When the lymphatic system becomes congested excess cellular waste and proteins (parts of cells, fibrin, and other debris) can build in any part of the body and brain, limiting circulation and function, similar to a log jam clogging a river. Activating the lymphatic system may help remove excess cellular waste by improving circulation and natural detoxification in the body and brain.

First Phase of ASD Lymph-Brain Study

The first phase of the study will concentrate on children with ASD, six and younger. Participants receive one month of manual LymphPractic sessions. We will manually activate the lymphatic system in a specific manner, two times a week for four weeks to help improve the lymph-brain connection. 


Your child will receive one month of LymphPractic sessions (approximately 8 sessions, around 45 minutes each). Sessions are fully clothed. Parents of young children, if needed bring a few toys, tablet, or phone,  to occupy your child during the session. The parent must be in the room with the therapist.

Our goal is to start a series of LymphPractic sessions twice a week over four weeks This greatly improves whole body and brain lymph flow, circulation and natural detoxification. When sessions are started your child may experience a worsening of particular traits for a few hours to a day after the first session. This occurs as released waste congests the organs and central nervous system after the session. We hope to avoid this detox reaction by starting slow and teaching parents how to prepare their child for lymphatic therapy and how to activate their child's lymphatic system at home.

If you have any questions about our ASD-Lymphatic System Study, please contact us.